• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
  • All Recipes
  • About Me

Brew Buzz Blend logo

  • A spinach and pineapple smoothie served in a mason jar.
    Spinach and Pineapple Smoothie
  • Two glasses of vodka and coke sitting on a gold tray.
    Vodka and Coke
  • Three blue lagoon cocktails served in coupe glasses and garnished with fresh flowers.
    Blue Lagoon Cocktail
  • A dirty shirley cocktail garnished with lime slices and cherries.
    Dirty Shirley Cocktail
  • A royal flush cocktail garnished with a lemon slice sitting on a countertop.
    Royal Flush Drink
  • Best Fall Vodka Cocktails
  • Two French connection cocktails sitting on a metal tray.
    French Connection Cocktail
  • A glass of mezcal negroni sitting on a countertop.
    Mezcal Negroni
  • Two highball glasses filled with bay breeze cocktail and garnished with dried pineapple slices.
    Bay Breeze Cocktail (Hawaiian Sea Breeze)
  • A madras cocktail served in a high ball glass sitting next to a carafe of orange juice.
    Madras Cocktail
  • A southside cocktail served in a coupe glass and garnished with fresh mint leaves.
    Southside Cocktail
  • A bee's knees cocktail served in a coupe glass sitting on a counter.
    Bee's Knees Cocktail
Home » Cocktails

Published: May 19, 2025 by Tiffany · This post may contain affiliate links · Leave a Comment

15 Must-Try Mezcal Cocktails

If you love bold, smoky flavors in your drinks, you’re in for a treat with this collection of mezcal cocktails. Mezcal brings a rich, earthy depth that instantly elevates any cocktail—think of it as tequila’s cooler, moodier cousin.

From fresh citrusy sippers to fruity twists and a little heat here and there, these mezcal cocktails are perfect for happy hour, weekend get-togethers, or whenever you’re craving something a little different. They’re easy to make at home and guaranteed to impress—no fancy bar tools required.

A mezcalita served with a slice of dried pineapple sitting on a marble countertop.
Jump to:
  • What is Mezcal?
  • What is the difference between Mezcal and Tequila?
  • Must Try Mezcal Cocktails

What is Mezcal?

Mezcal is a distilled spirit made from the agave plant, and it’s been part of Mexican tradition for centuries—long before it became a bar menu favorite. While tequila is the most well-known version (made only from blue agave), mezcal can be made from many different agave varieties. That means the flavor can vary a lot depending on the type of agave used, where it’s grown, and how it’s made. Most mezcal still comes from Oaxaca, where small, family-run distilleries (called palenques) stick to traditional methods that go back generations—like roasting agave hearts in underground pits and distilling in clay or copper pots.

Even though mezcal has deep roots in Mexican culture, its official definition is a bit more recent. For a bottle to be legally labeled as mezcal, it has to be made in one of a handful of designated Mexican states and certified by a regulatory organization. But don’t let labels fool you—true mezcal is about process and tradition. The best bottles aren’t just smoky and complex, they also tell a story of the land and the people who made them. It’s a spirit that’s meant to be sipped slowly and shared—preferably with good company.

A glass of mezcal negroni sitting on a countertop.

What is the difference between Mezcal and Tequila?

Tequila and mezcal are both made from agave, but tequila is actually a specific type of mezcal. Tequila can only be made from blue agave and in certain regions, mostly around Jalisco, while mezcal can be made from a variety of agave types and is produced in several Mexican states—Oaxaca being the most well-known.

The big difference comes down to production. Mezcal is usually made using traditional methods like roasting agave in underground pits, which gives it that signature smoky flavor. Tequila is often produced with more modern, industrial techniques and is commonly aged, while mezcal is typically enjoyed unaged to highlight the agave itself.

Must Try Mezcal Cocktails

Here is a versatile list of some of the best Mezcal cocktails that are worth trying. Grab a bottle of your favorite Mezcal and let's get mixing!

1
Two mezcalitas garnished with pineapple slices sitting on a gold tray.
Mezcalita
A Mezcalita is a refreshing margarita-style cocktail made with smokey mezcal and orange juice. This bright, fruity drink is served with a spicy rim and is definitely an easy and flavorful sip!
Mezcalita
2
A mezcal sour cocktail served in a coupe glass sitting on a marble tray.
Mezcal Sour
A Mezcal Sour is smokey, tangy, and deliciously smooth. This cocktail is a refreshing and silky sip that is easy to make with a creamy foam topping!
Mezcal Sour
3
A glass of mezcal negroni sitting on a countertop.
Mezcal Negroni
A classic cocktail gets a new, smokey twist with a Mezcal Negroni! This tasty drink is full of well-balanced flavor and may just be the best Negroni of all.
Mezcal Negroni
4
Mezcal Paloma
thesageapron.com
Mezcal Paloma
This Mezcal Paloma puts a smoky spin on the classic cocktail by swapping in mezcal for tequila, then mixing it with fresh grapefruit juice, lime juice, and agave syrup for a bright, citrus-forward drink. Topped with sparkling water and served over ice, it’s a refreshing balance of tart, sweet, and smoky flavors.
Mezcal Paloma
5
An old fashioned cocktail made with mezcal sitting on a tray.
uglyducklingbaker.com
Oaxaca Old Fashioned
This Oaxaca Old Fashioned is a smoky, spirit-forward twist on the classic cocktail, made with a mix of reposado tequila and mezcal, plus a touch of agave syrup and Angostura bitters. Smooth, complex, and easy to make, it’s a bold sipper that highlights the rich flavors of agave spirits.
Oaxaca Old Fashioned
6
A mezcal white negroni served with an orange twist on a black countertop.
thesageapron.com
Negroni Fumo Blanco
The Negroni Fumo Bianco is a creative take on the classic Negroni, blending mezcal, dry vermouth, and Suze for a smoky, bittersweet twist. With its pale hue and layered flavor, this white Negroni variation is both elegant and unexpected.
Negroni Fumo Blanco
7
A mezcal chocolate cherry cocktail sitting on a marble counter.
Mezcal Chocolate Cherry
The Mezcal Chocolate Cherry cocktail blends mezcal, maraschino liqueur, and chocolate bitters, with an optional touch of butter-washed, cocoa-infused rum for extra richness. Smoky, subtly sweet, and layered with dark, complex flavors, it’s a creative and sophisticated drink with a dessert-like edge.
Mezcal Chocolate Cherry Cocktail
8
Pineapple Mezcal Cocktail
thelittlestcrumb.com
Pineapple Mezcal Cocktail
This Pineapple Mezcal Cocktail is a tropical and smoky drink made with mezcal, pineapple juice, lime juice, and simple syrup for a refreshing yet bold flavor profile. Easy to shake up and perfect for summer, it’s a vibrant cocktail with just the right balance of sweetness and smoke.
Pineapple Mezcal Cocktail
9
muybuenoblog.com
Jalapeño Watermelon Margarita (Spicy Mezcal Margarita)
The Frida Mezkahlo Margarita is a bold and colorful cocktail made with mezcal, hibiscus syrup, lime juice, and orange liqueur, offering a smoky, floral twist on the classic margarita. Inspired by Frida Kahlo, it’s a striking drink both in flavor and appearance, finished with a vibrant hibiscus salt rim.
Jalapeno Watermelon Margarita
10
A moody black heart cocktail in a festive coupe glass sitting on a counter.
The Black Heart
The Black Heart Halloween Cocktail is a rich and complex drink made with genever, mezcal, Chambord, lingonberry syrup, maple syrup, and chocolate bitters. Dark, fruity, and smoky with layered sweetness, it’s a dramatic and flavorful cocktail crafted for spooky season vibes.
Black Heart Cocktail
11
Frozen Mezcal Margarita
flavormosaic.com
Frozen Mezcal Margarita
The frozen mezcal margarita blends mezcal, lime juice, and orange liqueur, with ice for a smoky, slushy twist on the classic cocktail. It's a refreshing and bold drink with just the right balance of citrus and smoke, perfect for hot days or entertaining.
Frozen Mezcal Margarita
12
Fire and Brimstone Cocktail
The Fire and Brimstone cocktail combines mezcal, triple sec, fresh lemon juice, agave syrup, and jalapeño slices for a smoky, citrusy drink with a subtle tea note and a hint of heat. Complex yet balanced, it’s a bold cocktail that layers spice, smoke, and brightness in every sip.
Fire and Brimstone Cocktail
13
Ultima Palabra Cocktail
The Ultima Palabra is a smoky, modern twist on the classic Last Word cocktail, blending mezcal, green Chartreuse, maraschino liqueur, and fresh lime juice. With its bold herbal notes and a touch of citrus, this drink delivers a complex, balanced flavor with a memorable finish.
Ultima Palabra
14
Smoked Mezcal Manhattan
The Mezcal Manhattan is a smoky spin on the classic cocktail, made with mezcal, sweet vermouth, and Angostura bitters for a bold, complex flavor profile. Stirred and served over ice with a cherry garnish, it’s a rich, spirit-forward drink perfect for slow sipping.
Mezcal Manhattan
15
Gun Metal Blue Cocktail
The Gun Metal Blue Cocktail combines mezcal, blue curaçao, peach brandy, lime juice, cinnamon syrup, and a dash of Suze for a complex drink that’s smoky, citrusy, and slightly spiced. With its bold blue hue and layered flavor, it’s an inventive cocktail that’s as striking in appearance as it is in taste.
Gun Metal Blue Cocktail

Reader Interactions

Leave a Comment Cancel reply

Your email address will not be published. Required fields are marked *

Recipe Rating




Primary Sidebar

Portrait of Tiffany Welsh.

Hi, I'm Tiffany!

I love cooking, baking and trying new recipes. This space is all about sharing ideas for cocktails, mocktails, coffee, juice and smoothies. Anything that will quench your thirst!

Learn More About Me

Most Recent

  • A spinach and pineapple smoothie served in a mason jar.
    Spinach and Pineapple Smoothie
  • Two glasses of vodka and coke sitting on a gold tray.
    Vodka and Coke
  • Three blue lagoon cocktails served in coupe glasses and garnished with fresh flowers.
    Blue Lagoon Cocktail
  • A dirty shirley cocktail garnished with lime slices and cherries.
    Dirty Shirley Cocktail
  • A royal flush cocktail garnished with a lemon slice sitting on a countertop.
    Royal Flush Drink
  • Best Fall Vodka Cocktails

Footer

↑ back to top

Privacy Policy

Accessibility Policy



About

Copyright ©2025 BrewBuzzBlend